| Cat # | Size | Price | Quantity | |
|---|---|---|---|---|
| 111305 | 25 tests | $80 | ||
| 111306 | 100 tests | $170 |
| Clone | C398.4A-Rec |
|---|---|
| Application | FC |
| Reactivity | Human, mouse, rat |
| Format | iF488 |
| Target Name | CD278, ICOS, Inducible Costimulatory molecule |
| Isotype | Mouse IgG1 |
| Antibody Type | Monoclonal |
| Regulatory Status | RUO |
| Formulation | Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA |
| Protein Concentration | Supplied at a lot-specific concentration. |
| Storage&Handling | The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze. |
| Recommended Usage | For flow cytometric staining, it is recommended to use 5 uL of this reagent per 0.5-1.0 million cells in a 100 µL volume. Optimal reagent performance should be determined by titration for each specific application. |
| Excitation Laser | Blue Laser (488 nm) |
ICOS is a 47–57 kDa costimulatory molecule homologous to CD28/CTLA-4 and is expressed on activated T cells and a subset of thymocytes. Engagement of ICOS enhances T cell proliferation, promotes cytokine production such as IL-4 and IL-10, and plays an important role in humoral immunity and Th2 cell differentiation.
iF488 Anti-human/mouse/rat CD278 (ICOS) TDS
iF488 Mouse IgG1 Isotype Control
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