| Cat # | Size | Price | Quantity | |
|---|---|---|---|---|
| 203103 | 25 tests | $80 | ||
| 203104 | 100 tests | $180 |
| Clone | N418-mG1 |
|---|---|
| Application | FC |
| Reactivity | Mouse |
| Format | iF647 |
| Target Name | CD11c, integrin αX chain, CR4, ITGAX, p150 |
| Isotype | Mouse IgG1 |
| Antibody Type | Monoclonal |
| Regulatory Status | RUO |
| Formulation | Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA |
| Protein Concentration | Supplied at a lot-specific concentration. |
| Storage&Handling | The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze. |
| Recommended Usage | For flow cytometric staining, it is recommended to use 5 uL of this reagent per 0.5-1.0 million cells in a 100 µL volume. Optimal reagent performance should be determined by titration for each specific application. |
| Excitation Laser | Red Laser (633 nm) |
CD11c (Integrin αX, CR4, p150) is a ~150 kDa type I transmembrane glycoprotein that pairs non-covalently with β2 integrin (CD18) to form the αXβ2 heterodimer. It is expressed mainly on dendritic cells, with additional expression on NK cells, subsets of intestinal intraepithelial lymphocytes, monocytes/macrophages, granulocytes, and some activated T and B cells. CD11c/CD18 binds iC3b, fibrinogen, and CD54 (ICAM-1), mediating cell–cell adhesion, phagocytosis of opsonized particles, and immune cell trafficking.
iF647 Mouse IgG1 Isotype Control
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